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Talk to your healthcare provider to see if your heart is strong enough for sex. If you feel chest pain, dizziness, or nausea during sex, stop and contact your healthcare provider right away. Sildenafil may cause a mild and temporary drop in blood pressure.
Keep VIAGRA and all medicines out of the reach of children. Single doses of antacid (magnesium hydroxide/aluminum hydroxide) did not affect the bioavailability of VIAGRA. Sildenafil is cleared predominantly by the CYP3A4 (major route) and CYP2C9 (minor route) hepatic microsomal isoenzymes. The major circulating metabolite results from Ndesmethylation of sildenafil, and is itself further metabolized. This metabolite has a PDE selectivity profile similar to sildenafil and an in vitro potency for PDE5 approximately 50% of the parent drug. Plasma concentrations of this metabolite are approximately 40% of those seen for sildenafil, so that the metabolite accounts for about 20% of sildenafil’s pharmacologic effects.
Therefore, PDE5 inhibitors, including VIAGRA, shouldbe used with caution in these patients and only when the anticipated benefitsoutweigh the risks. Analysis of the safety database from controlled clinical trials showed no apparent difference in adverse reactions in patients taking VIAGRA with and without antihypertensive medication. This analysis was performed retrospectively, and was not powered to detect any pre-specified difference in adverse reactions. For most patients, the recommended dose is 50 mg taken, BUY XANAX WITHOUT PRESCRITION as needed, approximately 1 hour before sexual activity.
Aprodastil (prostaglandin E1) is being tried as an intraurethral pessary and as topical gel. There are a number of trials going on for use of Sildenafil in women to enhance the sexual experience. It is well known that women also have erectile tissues and many scientists have come to believe that the causes of male and female impotence may not be that far apart after all. Currently Phase II trials are on in Europe for use of Sildenafil for women.
Some side effects can be serious. If you experience any of the following symptoms, call your doctor immediately:
The studies were done in men above age of 18 who were diagnosed to be suffering from erectile dysfunction both organic and psychogenic. Efficacy was assessed by using responses to question three (frequency of penetration) and question four (maintenance of erection after penetration) of 15 question International Index of Erectile Function questionnaire [13]. The responses to the above questions were rated on a scale of 1 (almost never or never) to 5 (almost always or always). Many of the studies included interviews with the sexual partners.
Generic oral tablets are available for both conditions, but the brand-name drugs each treat only one of the conditions. Sildenafil oral tablet is available as the brand-name drugs Viagra and Revatio. Generic drugs usually cost less than the brand-name version. In some cases, they may not be available in every strength or form as the brand-name drug. Even if a drug contains the right medicine, it may not be the right dose.
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It’s not known how long Viagra’s effects may last in females, because the drug isn’t approved for use in females. More studies are needed to know about Viagra use in females and how long it may last. So currently, there’s not enough information to know for sure if Viagra is safe or effective in females. If you’d like to know more about how Viagra affects females, talk with your doctor. If Viagra doesn’t seem to work for you, talk with your doctor.
Cialis 5-mg daily dosing is the only PDE5 inhibitor dose approved for treating an enlarged prostate; improving ED symptoms is an added benefit of the daily dose. Talk with your doctor about other drug options that may work for you. When filling your prescription, be sure to call ahead to make sure your pharmacy carries it. You should not need a new prescription for this medication to be refilled. Your doctor will write the number of refills authorized on your prescription. Talk with your doctor if you’re pregnant or planning to become pregnant.
You can only get VIAGRA by prescription from your doctor or healthcare provider.
Be sure to tell your doctor about any medical conditions you have and any medications you take before starting Viagra. If you have questions about how to pay for your prescription, talk with your doctor or pharmacist. Viagra may not be right for you if you have certain medical conditions or other factors that affect your health. Talk with your doctor about your health history before you take Viagra.