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<br><br><br>此类药物适用于保留部分直肠的手术,可以减少腺瘤性息肉的数目和大小。 总的来说,TPC、IPAA和IRA被认为是安全、低术后并发症和具有可接受的功能保留的术式。 然而,不同的术式有不同的适应症,不同的中心可能会有选择的偏好。<br>肿瘤易感性基因的携带者经常生活于一种心理上的不稳定状态,因此,解除患者的对癌症的焦虑通常被引用为预防性手术的原因。 对于带有高度肿瘤发生风险的基因突变的家族性腺瘤性息肉病,手术是唯一有效降低肿瘤发生和减轻患者肿瘤相关焦虑的方法。 在患者年龄较轻时即可用软性乙状结肠镜检查来指导手术介入的时机。 APC基因携带者中的结直肠癌通常不出现在婴儿期及青春早期。 带有已知APC基因突变的患者、FAP患者或已知APC基因突变患者的一级亲属,在10~12岁开始接受软性的乙状结肠镜检查。 如果发现结肠息肉或有已知的APC基因突变,必须继续随访并每年行结肠镜检一次。<br>对于肝纤维化,在肝硬化的外周区域,发现肝星状细胞中FAP表达升高。 [https://www.webopedia.com/crypto-gambling/casinos/guides/how-do-crypto-casinos-work/ DOWNLOAD WINDOWS 11 CRACKED] 此外,先前在心脏MRI中检测到的梗死区域在FAPI PET中未显示示踪剂摄取,这可能是由于在瘢痕成熟过程中激活的成纤维细胞大幅减少,这为区分新鲜缺血和成熟缺血提供了基础。 ¹⁸F-FDG是目前肿瘤PET显像中应用最广泛的放射性示踪剂,但也存在一定的不足。<br><br>
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