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<br><br><br>If you experience too many side effects with the 10 mg starting dose, your doctor may decrease it to 5 mg before sexual activity. For details about the side effects of tadalafil, see the "Side effects" section of this article. If you take tadalafil for pulmonary arterial hypertension, do not take Cialis® or other PDE5 inhibitors,  [https://www.medfielddiagnostics.com/ BUY XANAX WITHOUT PRESCRITION] including sildenafil (Revatio® or Viagra®) or vardenafil (Levitra®). If you take too much tadalafil or take it together with these medicines, the chance for side effects will be higher. When using this medicine for erectile dysfunction, the ability to have sexual activity may be improved for up to 36 hours after taking the tablet.<br>Warnings for people with certain health conditions<br>If you think this could be the case for you, talk to your GP who might recommend counselling or behavioural support therapy. However, if used incorrectly to boost sexual performance there could be a possibility of negative side effects and psychological dependence. Our clinical team is here to support you; please contact us through your online patient record if you'd like to discuss any side effects you're experiencing.<br>If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.<br>It is important to tell your doctor about any heart problems you have now or may have had in the past. This medicine can cause serious side effects in patients with heart problems. This medicine does not protect you against sexually transmitted diseases (including HIV or AIDS). Use protective measures and ask your doctor if you have any questions about this. Using this medicine with any of the following is usually not recommended, but may be unavoidable in some cases. Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases.<br><br>Safety and efficacy in patients below the age of 18 year shave not been established. Patients with left ventricular outflow obstruction, (e.g., aortic stenosis and idiopathic hypertrophic subaorticstenosis) can be sensitive to the action of vasodilators, including PDE5 inhibitors. Tadalafil had no significant effect on exposure (AUC) to S-warfarin or R-warfarin, nor did tadalafil affect changes in prothrombin time induced by warfarin. Simultaneous administration of an antacid (magnesium hydroxide/aluminum hydroxide) and tadalafil reduced the apparent rate of absorption of tadalafil without altering exposure (AUC) to tadalafil.<br>Other [https://www.blogher.com/?s=risk%20factors risk factors] for NAION, such as the presence of "crowded" optic disc, may have contributed to the occurrence of NAION in these studies. Therefore, patients who experience anginal chest pain after taking CIALIS should seek immediate medical attention. Although specific interactions have not been studied, other CYP3A4 inhibitors, such as erythromycin, itraconazole, and grapefruit juice, would likely increase tadalafil exposure. CIALIS is a substrate of and predominantly metabolized by CYP3A4.<br>Dosing<br>Partial, temporary, or permanent decrease or loss of vision in one or both eyes has been rarely reported. Once a day dosing of CIALIS may be useful to men who anticipate having sexual activity two or more times per&nbsp;week. Some men  taking CIALIS in clinical studies have reported dizziness.<br>In most cases, muscle pain caused by Cialis was mild or moderate and went away on its own within 48 hours. Muscle pain due to Cialis generally affects your lower back, buttocks, and thigh muscles. If you get an erection that lasts more than 4 hours, get medical help right away. Priapism must be treated as soon as possible or lasting damage can happen to your penis, including the inability to have erections. Two studies were conducted to assess the efficacy of CIALIS at a given timepoint after dosing, specifically at24 hours and at 36 hours after dosing. Three clinical pharmacology studies were conducted with tadalafil and doxazosin, an alpha[1]-adrenergic blocker.<br>In patients with mild or moderate hepatic impairment, the dose of CIALIS should not exceed 10 mg. Physicians should discuss with patients the potential for CIALIS to augment the blood-pressure-lowering effect of alpha-blockers and anti hypertensive medications [see DRUG INTERACTIONS and CLINICAL PHARMACOLOGY] . An observational case-crossover study evaluated the risk of NAION when PDE5 inhibitor use, as a class, occurred immediately before NAION onset (within 5 half-lives), compared to PDE5 inhibitor use in a prior time period. The results suggest an approximate 2-fold increase in the risk of NAION, with a risk estimate of2.15 (95% CI 1.06, 4.34). A similar study reported a consistent result, with a risk estimate of 2.27 (95% CI0.99, 5.20).<br>For occasional (as needed) use for ED, take one Cialis tablet at least 30 minutes before anticipated sexual activity. You should not take any additional doses of Cialis for occasional use before sexual activity. When Cialis is prescribed along with the drug finasteride for BPH, the recommended Cialis dose for once daily use is 5 mg, taken at approximately the same time every day for up to 26 weeks. (An active ingredient is what makes a medication work.) Cialis belongs to a group of drugs called phosphodiesterase type 5 inhibitors. Cialis is primarily used to treat erectile dysfunction (ED) in men, helping them achieve and maintain an erection during sexual activity. So consuming alcohol while taking this drug may increase your risk of having very low blood pressure.<br><br>